Impact of bacterial resistance on the choice of antibiotics in odontology: a review of current trends

Authors

DOI:

https://doi.org/10.47606/ACVEN/MV0227

Keywords:

Bacteriology, Odontology, Epidemiology

Abstract

Introduction: The repeated exposure of different bacteria to various groups of antibiotics has caused a representative increase in antimicrobial resistance, constituting a global public health problem. Objective: Describe the impact of bacterial resistance on the choice of antibiotics in dentistry: a review of current trends. Materials and methods: A narrative, non-systematic review was applied regarding the impact of bacterial resistance on the choice of antibiotics in dentistry, which included 34 scientific works, made up of observational studies, reports and review articles. The search and collection of information was carried out in the databases: PubMed, Medline, Google Scholar, Science Direct and Scopus-Elsevier, during November and December 2023. Results: Antimicrobial resistance is due to some mechanisms specific to cells. bacteria such as: elimination of antibiotics by cell membrane extrusion pumps, reduction in the absorption of antimicrobials, enzymes that generate the inactivation or degradation of antibiotics, as well as mutations or alterations in the target site of the antibiotics, so it is The application of innovative strategies is necessary to counteract the growing bacterial resistance. Conclusion: The ability of bacteria in the oral cavity to form dental biofilms creates a habitat conducive to genetic exchange, which favors the transmission of resistance genes. Therefore, alternative strategies are currently being developed, which include antimicrobial and antibiofilm agents. Scientific research becomes an imperative need to address this therapeutic challenge in the dental field.

Downloads

Download data is not yet available.

References

Aghamohammad, S., & Rohani, M. Antibiotic resistance and the alternatives to conventional antibiotics: The role of probiotics and microbiota in combating antimicrobial resistance. (2023). Microbiological https://doi.org/10.1016/j.micres.2022.127275

Fariña, N. Resistencia bacteriana: un problema de salud pública mundial de difícil solución. Mem. Inst. Investig. Cienc. Salud;14(1) (2016).:4-5.

Gastelo, R, Maguiña, C. Mecanismos de resistencia bacteriana. Rev Diagnóstico, 57(2) (2018), 82-6.

Goyes Baca, M, Sacon, M, & Poveda, F. X. Manejo del sistema de salud de Ecuador frente a la resistencia antimicrobiana. Revista Información Científica, (2023). 102, 1-14.

Patiño Bello D, Pérez Acevedo L, Torres Caycedo M, Rosas Leal D, Di Filippo Iriarte G. Uso de biocidas y mecanismos de respuesta bacteriana. Revista Cubana de Investigaciones Biomédicas [Internet]. 2019 [citado 23 Mar 2024]; 37 (3) Disponible en: https://revibiomedica.sld.cu/index.php/ibi/article/view/136

World Health Organization. Antimicrobial Resistance: (2014). Global Report on Surveillance.

Govindaraj A., Vanitha A. WHO global priority pathogens list on antibiotic resistance: an urgent need for action to integrate One Health data. Perspect Public Health. (2018). 138:87-8.

Camou, T, Zunino, P, Hortal, M, Camou, T, Zunino, P, & Hortal, M. Alarma por la resistencia a antimicrobianos: Situación actual y desafíos. Revista Médica del Uruguay, (2017). 33(4), 104-127.

Contreras, B. Reporte de datos de resistencia a los antimicrobianos en Ecuador Min Salud Pub. (2018). 2(1):1-10. Disponible en: https://www.salud.gob.ec/wpcontent/uploads/2019/08/gaceta_ram2018. Pdf

Li, T, Wang, Z, Guo, J, de la Fuente Nunez, C, Wang, J, Han, B, Tao, H, Liu, J, & Wang, X Bacterial resistance to antibacterial agents: Mechanisms, control strategies, and implications for global health. Science of The Total Environment, (2023). 860, 160461. https://doi.org/10.1016/j.scitotenv.2022.160461

Urquizo Ayala, G., Arce Chuquimia, J, & Alanoca Mamani, G Resistencia bacteriana por beta lactamasas de espectro extendido: un problema creciente. Revista Médica La Paz, (2018). 24(2), 77-83.

Bush, K, & Jacoby, G A Updated functional classification of Blactamases Antimicrobial agents and chemotherapy, (2010). 54(3), 969-976.

González, J, Maguiña, C, González, F La resistencia a los antibióticos: un problema muy serio. Acta Médica Peruana, (2019). 36(2), 145-151.

Darby, E. M, Trampari, E, Siasat, P, Gaya, M. S, Alav, I, Webber, M A, & Blair, J M A Molecular mechanisms of antibiotic resistance revisited. Nature Reviews Microbiology, (2022). 21, 280-295. https://doi.org/10.1038/s41579-022-00820-y

Schaenzer, A. J, & Wright, G. D. Antibiotic Resistance by Enzymatic Modification of Targets. Trends in Molecular Medicine, (2020). 26, 768-782. https://doi.org/10.1016/j.molmed.2020.05.001

Davies J, Davies D. Origins and Evolution of Antibiotic resistance. Microbiol Mol Biol Rev. (2010). 74(3):417-33. https://doi:10.1128/MMBR.00016-10

Ministerio de Salud Pública. Plan Nacional para la Prevención y Control de la Resistencia Antimicrobiana (RAM) 2019-2023. Ecuador. (2019). Disponible en: https://www.salud.gob.ec/msp-presento plan-nacional-para-la-prevencion-y-control de-la-resistencia-antimicrobiana-ram-2019 2023/

Al Nawas, B., & Ziegler A. Los antibióticos en odontología. Revista Quintessence, (2009). 60(12):1425-37. Disponible en: https://www.elsevier.es/es-revista-quintessence-9-pdf-X0214098511068667

Flores, J, Aguilar S. Antimicrobianos en odontología: resultados de una encuesta sobre el tratamiento y prevención de infecciones, la profilaxis de endocarditis infecciosa y la combinación de antibióticos. Revista ADM /Enero-Febrero 2012/VOL .LXIX. NO.1. P. (2012). 22-30. Disponible en: https://eds.s.ebscohost.com/eds/pdfviewer/pdfviewer?vid=2&sid=25ed8646-2adf-41f5-b782-9610c7c94733%40redis

Lemos JA, Palmer SR, Zeng L, Wen ZT, Kajfasz JK, Freires IA, Abranches J, Brady LJ. The Biology of Streptococcus mutans. Microbiol Spectr. Jan; (2019). 7(1):10.1128/microbiolspec.GPP3-0051-2018. doi: 10.1128/microbiolspec.GPP3-0051-2018.

Alves Barroco C, Rivas García L, Fernandes AR, Baptista PV. Tackling Multidrug Resistance in Streptococci - From Novel Biotherapeutic Strategies to Nanomedicines. Front Microbiol. Oct (2020) 6;11:579916. doi: 10.3389/fmicb.2020.579916.

Xu W, Zhou W, Wang H, Liang S. Roles of Porphyromonas gingivalis and its virulence factors in periodontitis. Adv Protein Chem Struct Biol. (2020). 120:45-84. doi: 10.1016/bs.apcsb.2019.12.001.

Prachi Sao, Siddharth Vats, Sachidanand Singh. Porphyromonas gingivalis resistance and virulence: An integrated functional network analysis, Gene, Volume 839, (2022). 146734, ISSN 0378-1119, https://doi.org/10.1016/j.gene.2022.146734.

Kim M, Yun SY, Lee Y, Lee H, Yong D, Lee K. Clinical Differences in Patients Infected with Fusobacterium and Antimicrobial Susceptibility of Fusobacterium Isolates Recovered at a Tertiary Care Hospital in Korea. Ann Lab Med. Mar 1;42(2022). (2):188-195. doi: 10.3343/alm.2022.42.2.188.

Bhat KG, Khot P, Patil S, Pattar G, Majukar S. Antimicrobial susceptibility pattern of oral isolates of Aggregatibacter actinomycetemcomitans. J Oral Maxillofac Pathol. (2019) May Aug;23(2):231-235. doi: 10.4103/jomfp.JOMFP_123_19.

Kwack KH, Jang EY, Yang SB, Lee JH, Moon JH. Genomic and phenotypic comparison of Prevotella intermedia strains possessing different virulence in vivo. Virulence. Dec; (2022). 13(1):1133-1145. doi: 10.1080/21505594.2022.2095718.

Hammami C, Nasri W. Antibiotics in the Treatment of Periodontitis: A Systematic Review of the Literature. Int J Dent. Nov (2021). 8;2021:6846074. doi: 10.1155/2021/6846074.

Castillo Y, Delgadillo NA, Neuta Y, Hernández A, Acevedo T, Cárdenas E, Montaño A, Lafaurie GI, Castillo DM. Antibiotic Susceptibility and Resistance Genes in Oral Clinical Isolates of Prevotella intermedia, Prevotella nigrescens, and Prevotella melaninogenica. Antibiotics (Basel). 2022 Jul 4;11(7):888. doi: 10.3390/antibiotics11070888. PMID: 35884141; PMCID: PMC9312306.

Zeng H, Chan Y, Gao W, Leung WK, Watt RM. Diversity of Treponema denticola and Other Oral Treponeme Lineages in Subjects with Periodontitis and Gingivitis. Microbiol Spectr. (2021). Oct 31;9(2):e0070121. doi: 10.1128/Spectrum.00701-21.

Okamoto Shibayama K, Sekino J, Yoshikawa K, Saito A, Ishihara K. Antimicrobial susceptibility profiles of oral Treponema species. Anaerobe. Dec; (2017)48:242-248. doi: 10.1016/j.anaerobe.2017.10.005. Epub 2017 Oct 13. PMID: 29030100.

Sharma A. Virulence mechanisms of Tannerella forsythia. Periodontol 2000. 54(1): (2010). 106-16. doi: 10.1111/j.1600-0757.2009.00332.x. PMID: 20712636; PMCID: PMC2934765.

Ardila CM, Bedoya García JA. Antimicrobial resistance of Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis and Tannerella forsythia in periodontitis patients. J Glob Antimicrob Resist. Sep;22: (2020). 215-218. doi: 10.1016/j.jgar.2020.02.024.

Castellano González Maribel, Perozo Mena Armindo, Gutiérrez S Kimberly, Jiménez S Jessica, Urdaneta E María. Distribution of species and antimicrobial susceptibility in Enterococcus strains of clinical origin. Kasmera, vol. 46, núm. 2, (2018). pp. 99-115.

Dioguardi, M.; Crincoli, V; Laino, L.; Alovisi, M.; Sovereto, D.; Lo Muzio, L.; Troiano, G. Prevalence of Bacteria of Genus Actinomyces in Persistent Extraradicular Lesions Systematic Review. J. Clin. Med, 9, (2020). 457. https://doi.org/10.3390/jcm9020457

De Simeis D, Serra S. Actinomycetes: A Never-Ending Source of Bioactive Compounds An Overview on Antibiotics Production. Antibiotics (Basel). Apr 22; 10 (2021). (5):483. doi: 10.3390/antibiotics10050483. PMID: 33922100; PMCID: PMC8143475.

Wolff A, Rodloff AC, Vielkind P, Borgmann T, Stingu CS. Antimicrobial Susceptibility of Clinical Oral Isolates of Actinomyces spp. Microorganisms. (2022). 7;10(1):125. doi: 10.3390/microorganisms10010125. PMID: 35056574; PMCID: PMC8779083.

Published

2024-04-06

How to Cite

Santaella Palma, L. E., Bazurto Quinteros, M. J., & Ramírez Sánchez, K. M. (2024). Impact of bacterial resistance on the choice of antibiotics in odontology: a review of current trends. Más Vita, 6(1), 55–72. https://doi.org/10.47606/ACVEN/MV0227

Issue

Section

Original Articles